Does Intraarticular Inflammation Predict Biomechanical Cartilage Properties?
نویسندگان
چکیده
منابع مشابه
Imaging the Biomechanical Properties of Articular Cartilage
Function: The primary function of articular cartilage is mechanical: under load it must deform to distribute the load over a larger area so as to minimize stress in the underlying bone. In addition, articular cartilage must provide a very low friction surface for gliding when the joint is flexed so that articulating joints move freely. Lastly, it must carry out these two functions for a lifetim...
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OBJECTIVE An early hallmark of osteoarthritis (OA) is the progressive loss of glycosaminoglycans (GAGs), the extracellular matrix (ECM) component of articular cartilage that confers it with compressive stiffness. Our aim in this work is to establish the feasibility of using Contrast Enhanced Computed Tomography (CECT) with an anionic iodinated contrast agent - Cysto Conray II - as a minimally i...
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Tissue behavior is governed to a large extent by composition and microstructure of the extracellular matrix. In cartilage, various biopolymers (glycosaminoglycans, collagen, hyaluronic acid, etc.) are integrated into a complex network that imparts the tissue with its low-friction characteristics and load-bearing capacity. The structure of collagen (predominantly type II collagen) gives it tensi...
متن کاملDoes cartilage volume measurement or radiographic osteoarthritis at baseline independently predict ten-year cartilage volume loss?
BACKGROUND The aim of this study was to examine whether cartilage volume as measured by MRI and radiographic osteoarthritis (OA) at baseline predict cartilage volume loss over ten years independent of each other and other structural co-pathologies. METHODS 219 participants [mean-age 45(26-61); 57 % female] were studied at baseline and ten years. Approximately half were the adult offspring of ...
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ژورنال
عنوان ژورنال: Clinical Orthopaedics & Related Research
سال: 2014
ISSN: 0009-921X
DOI: 10.1007/s11999-014-3583-0